Takeaways:
- GLP-1 medications can be life-changing, but digestive side effects can make it hard to stick with treatment.
- Oshi’s GI specialists work together to help you manage side effects, uncover potential hidden digestive concerns, and feel your best on GLP-1s.
- Fast, personalized care and ongoing support mean you’re never left to manage symptoms on your own.
Taking a GLP-1 medication like Ozempic or Wegovy can be a life-changing step toward managing diabetes or other health conditions. But if you’re struggling with digestive side effects, you’re not alone. Nearly 6 percent of adults now use GLP-1s, and side effects like nausea, constipation, and abdominal discomfort are common. In fact, up to 70 percent of people on GLP-1s report some kind of stomach trouble.
Many people find these side effects tough enough that they stop their medication before they see any benefits. But you don’t have to choose between your health and your comfort.
At Oshi, we can work with you to help you find relief from gastrointestinal (GI) symptoms—whether they’re the result of a digestive condition or a medication side effect.
Understanding GLP-1 side effects
If you’re taking a GLP-1 medication, you might notice your body reacting in uncomfortable ways.
Common GI-related side effects include:
- Abdominal pain
- Constipation
- Bloating
- Diarrhea
- Nausea
- Vomiting
GLP-1 medications slow down how fast food moves through your digestive system. This helps control blood sugar and appetite, but it can also leave your gut feeling unsettled.
These medications can even trigger flare-ups of GI conditions like heartburn or gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), hemorrhoids, gastritis, ulcers, or other digestive issues.
As your dose increases, you might notice your symptoms get worse. But with the right approach, relief is possible.
The provider was friendly, knowledgeable, and professional. I learned a lot and feel well-equipped to manage my symptoms.
— Oshi GLP-1 patient
Medical expertise, tailored to you
Oshi brings together a team of GI specialists, including GI providers, registered dietitians, and gut-brain specialists who all work together to help you feel better on GLP-1 medications. They’ll also provide clear guidance on what to expect with GLP-1s and what you can do to minimize side effects.
Your provider will screen you for any underlying digestive issues that could be making your symptoms worse, and they’ll adjust and tailor your medications for better symptom control. Over half of patients who come to us with GLP-1 side effects discover they have an underlying digestive health concern within their first few visits—and start treatment asap.
Ninety-six percent of Oshi patients achieve GLP-1-related GI symptom control, with symptom severity dropping by 91 percent.*
Personalized care for the whole you
Fast, easy access to care
With Oshi, you don’t have to wait weeks or months to get help with GLP-1 side effects. You can see a provider within days—even in the evenings or on weekends.
If your symptoms get worse, you have 24/7 access to your care team. You’re never left to figure things out on your own. You can reach out anytime for answers, support, or reassurance—no need for a stressful (and expensive) trip to the emergency room.
Dietary guidance that fits your life
Oshi registered dietitians can help you identify foods that could be making your GLP-1 side effects worse.
Dietary care at Oshi also includes teaching you practical ways to modify your diet so you can feel your best—without feeling deprived. Our dietitians can support you in making realistic gut-friendly changes that fit your cultural background, lifestyle, and health needs.
Gut-brain support
Side effects from GLP-1s can mess with your gut—and your life.
Oshi gut-brain specialists are here to help you manage the stress, anxiety, and frustration that may come with uncomfortable side effects.
They’ll work alongside you and the rest of your care team to:
- Teach you how stress and emotion can impact your digestion
- Share practical ways to manage heightened emotions that can make GI symptoms worse
- Build lasting habits to support your digestive health and overall well-being
You’ll also get science-backed tools to help you stick with your treatment plan and feel more confident in managing side effects.
Bottom line
Managing digestive side effects from GLP-1 medications can feel frustrating, but support is available. With Oshi, you get expert GI care tailored to your needs, practical strategies for relief, and a whole team by your side.
Frequently asked questions
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Yes. It’s possible to manage side effects and keep taking your prescribed medication. Your Oshi care team can help you find ways to cope with uncomfortable side effects and adjust your medication dosage or prescription if necessary.
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It’s common to have digestive side effects like nausea, constipation, or diarrhea when starting GLP-1s. Thankfully, these symptoms often improve over time, and there are effective ways to feel better, like eating smaller, more frequent meals and finding simple ways to manage stress. Oshi GI providers, registered dietitians, and gut-brain specialists are here to help you feel more comfortable as you navigate life on GLP-1s.
*Results obtained within a patient population who attended at least four visits with Oshi
Take charge of your gut health on GLP-1 medications with expert dietary support
If you’re taking a GLP-1 medication and experiencing side effects like nausea or digestive discomfort, you’re not alone. Our team of GI-specialized, registered dietitians is here to help.
Your nutrition plays an important role in how you feel day to day, especially when adjusting to a new medication. Oshi dietitians can work with you to:
✔ Ensure you stay nourished and offer practical tips for navigating common GLP-1 side effects
✔ Build personalized meal plans that fit your lifestyle and medication schedule
✔ Guide you through small, sustainable changes to help you feel your best
✔ And so much more!
Ready to make mealtimes less stressful and feel in control again?
